Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604182 | 0.87 | GPR88 (0.53) | PRKCAPRKCDSMN1; SMN2 | |
| SCHEMBL28918870 | 0.87 | GPR88 (0.53) | PRKCAPRKCDSMN1; SMN2 | |
| SCHEMBL28601780 | 0.86 | KMT2A (0.50) | SMN1; SMN2 | |
| SCHEMBL28609046 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2 | |
| SCHEMBL28594122 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2 | |
| SCHEMBL10410136 | 0.82 | LTA4H (0.52) | LTA4HALOX5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28608660 | 0.82 | L3MBTL1 (0.49) | — | |
| SCHEMBL28596422 | 0.82 | KMT2A (0.43) | NPC1 | |
| SCHEMBL28595878 | 0.80 | MTNR1A (0.46) | — | |
| SCHEMBL28601751 | 0.80 | MTNR1A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898213-A | Polysubstituted 1, 3-diene supported ring compound and application thereof | 中国科学院上海药物研究所 | 2021-06-04 | — | — | CN | disclosed |