Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647058 | 0.89 | CACNA1B (0.44) | TSHRMAOAMAOB | |
| SCHEMBL8391958 | 0.83 | CA1 (0.38) | EPHX2IDO1OPRM1L3MBTL1 | |
| SCHEMBL3294094 | 0.83 | MRGPRX4 (0.46) | NPC1RAB9ATRPM8 | |
| SCHEMBL5951078 | 0.81 | L3MBTL1 (0.35) | EPHX2OPRM1L3MBTL1TRPM8 | |
| SCHEMBL8393611 | 0.81 | MEN1 (0.43) | EPHX2IDO1OPRM1 | |
| SCHEMBL22782583 | 0.79 | CHRM1 (0.39) | L3MBTL1 | |
| SCHEMBL8396298 | 0.79 | OPRM1 (0.41) | OPRM1L3MBTL1 | |
| SCHEMBL27746943 | 0.79 | TSHR (0.33) | TSHREPHX2SMN1; SMN2TRPM8 | |
| SCHEMBL3287933 | 0.78 | ALDH1A1 (0.42) | OPRM1ALDH1A1 | |
| SCHEMBL8396229 | 0.78 | L3MBTL1 (0.43) | EPHX2OPRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912603-B | Practical method for synthesizing novel bioactive molecules by using N-methoxyamide as nitrogen source | 苏州大学 | 2021-08-03 | — | — | CN | disclosed |