Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.81 |
| ▸ | PTAFR | P25105 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344799 | 0.90 | HIF1A (1.00) | HIF1ANPC1RAB9ASMN1; SMN2FAAH | |
| SCHEMBL28607757 | 0.88 | HIF1A (1.00) | HIF1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28608835 | 0.82 | HIF1A (0.85) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28601911 | 0.82 | HIF1A (0.85) | HIF1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28601917 | 0.82 | HIF1A (1.00) | HIF1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28614480 | 0.82 | HIF1A (0.79) | HIF1AFAAHLMNA | |
| SCHEMBL28347634 | 0.81 | HIF1A (1.00) | HIF1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28601903 | 0.81 | HIF1A (0.83) | HIF1ANPC1RAB9AALDH1A1FAAH | |
| SCHEMBL28596560 | 0.81 | HIF1A (0.83) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28606401 | 0.80 | HIF1A (0.72) | HIF1AKMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |