Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344799 | 0.89 | HIF1A (1.00) | HIF1AMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28614480 | 0.88 | HIF1A (0.79) | HIF1AMAPTFAAHGCGR | |
| SCHEMBL28601911 | 0.86 | HIF1A (0.85) | HIF1AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL13210596 | 0.84 | HIF1A (0.72) | HIF1AMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8162947 | 0.84 | HIF1A (0.72) | HIF1AMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28601907 | 0.82 | HIF1A (0.81) | HIF1AKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28607757 | 0.81 | HIF1A (1.00) | HIF1AKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28608835 | 0.81 | HIF1A (0.85) | HIF1ANPC1RAB9AFAAHEGLN1 | |
| SCHEMBL28601903 | 0.81 | HIF1A (0.83) | HIF1AALDH1A1NPC1RAB9AFAAH | |
| SCHEMBL28347634 | 0.81 | HIF1A (1.00) | HIF1AKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |