Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATF1 | P18846 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859852 | 0.90 | CCR1 (0.49) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2850444 | 0.87 | CCR1 (0.46) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2854294 | 0.87 | CCR1 (0.48) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2857725 | 0.85 | MAPT (0.52) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2854321 | 0.79 | MAPT (0.53) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2854667 | 0.78 | ALDH1A1 (0.55) | CCR1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL13513684 | 0.75 | CCR1 (0.54) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2854529 | 0.74 | MAPT (0.47) | CCR1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL2850211 | 0.74 | MAPT (0.49) | CCR1KEAP1NFE2L2MAPTKMT2A | |
| SCHEMBL2862087 | 0.74 | MAPT (0.51) | CCR1KEAP1NFE2L2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |