Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA4 | P22748 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618883 | 0.89 | PTGES (0.47) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL28919583 | 0.81 | PTGES (0.46) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL28599278 | 0.80 | PTGES (0.45) | CA1CA2CA4CA9MEN1 | |
| SCHEMBL28402744 | 0.77 | LMNA (0.54) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28400696 | 0.75 | LMNA (0.60) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL28606683 | 0.73 | SPHK2 (0.42) | CA1CA2CA4CA9SPHK2 | |
| SCHEMBL7893587 | 0.72 | CA1 (0.62) | CA1CA2CA4CA9MEN1 | |
| SCHEMBL28236200 | 0.71 | KMT2A (0.64) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL29720703 | 0.70 | CA2 (0.43) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL28399007 | 0.70 | TSHR (0.53) | MEN1KMT2APOLBALDH1A1GLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105395-B | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | claimed |
| CN-113105395-A | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2021-07-13 | — | — | CN | claimed |
| CN-113105395-B | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113105395-A | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2021-07-13 | — | — | CN | disclosed |