Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566639 | 0.74 | CLK4 (0.42) | PDE3BPDE3AMAPTMEN1ALDH1A1 | |
| SCHEMBL14301805 | 0.73 | CYP1A2 (0.44) | PDE3BPDE3AGAAMAPTMEN1 | |
| SCHEMBL28411172 | 0.71 | RAB9A (0.37) | PDE3BPDE3AGAAMAPTMEN1 | |
| SCHEMBL14958066 | 0.70 | PDE3B (0.35) | PDE3BPDE3AGAAMAPTMEN1 | |
| SCHEMBL14957158 | 0.69 | PDE3B (0.34) | PDE3BPDE3AMAPTMEN1ALDH1A1 | |
| SCHEMBL12724876 | 0.66 | PIM1 (0.33) | PDE3BPDE3AMAPTMEN1ALDH1A1 | |
| SCHEMBL28995653 | 0.65 | KDM4E (0.35) | GAAMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL20504652 | 0.62 | CA1 (0.32) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL3294049 | 0.62 | KMT2A (0.35) | GAAMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL22598655 | 0.61 | PDE10A (0.33) | MAPTMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | claimed |