Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656769 | 0.86 | PARP1 (0.60) | PARP1ALDH1A1GAAPKML3MBTL1 | |
| SCHEMBL10948000 | 0.85 | VCAM1 (0.62) | PARP1ALDH1A1GAATSHRLMNA | |
| SCHEMBL2156916 | 0.85 | CES1 (0.54) | PARP1ALDH1A1GAATSHRLMNA | |
| SCHEMBL8625493 | 0.84 | VCAM1 (0.61) | ALDH1A1GAATSHRLMNAMAPT | |
| SCHEMBL99875 | 0.84 | CASP6 (0.70) | TSHRLMNACASP6 | |
| SCHEMBL1254186 | 0.83 | PARP1 (0.71) | PARP1ALDH1A1GAAPKML3MBTL1 | |
| SCHEMBL478142 | 0.82 | MAPT (0.56) | ALDH1A1GAAPKML3MBTL1TSHR | |
| SCHEMBL3892799 | 0.82 | ALDH1A1 (0.52) | PARP1ALDH1A1GAATSHRLMNA | |
| SCHEMBL29559211 | 0.82 | MAPT (0.56) | ALDH1A1GAAPKML3MBTL1TSHR | |
| Carbamic Acid SCHEMBL28096989 | 0.81 | MAPK1 (0.62) | ALDH1A1L3MBTL1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120000651-A | Application of beta-carboline compounds in preparation of medicines for preventing and/or treating acute lung injury | 中国人民解放军北部战区总医院 | 2025-05-16 | — | — | CN | disclosed |
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |
| CN-115232126-B | Beta-carbolin-1, 2, 3-triazole compound, preparation method thereof and application of compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-04-25 | — | — | CN | disclosed |
| CN-113072552-B | Beta-carboline GSK3 beta/DYRK 1A dual inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2022-11-04 | — | — | CN | disclosed |
| CN-113072552-A | Beta-carboline GSK3 beta/DYRK 1A dual inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2021-07-06 | — | — | CN | disclosed |