Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156916 | 0.87 | CES1 (0.54) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL10948000 | 0.87 | VCAM1 (0.62) | CASP6TSHRLMNA | |
| SCHEMBL8625493 | 0.85 | VCAM1 (0.61) | CASP6TSHRLMNA | |
| SCHEMBL2722394 | 0.85 | CASP6 (0.70) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL3892799 | 0.84 | ALDH1A1 (0.52) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL478142 | 0.84 | MAPT (0.56) | CASP6TSHRLMNA | |
| SCHEMBL28604140 | 0.84 | PARP1 (0.65) | CASP6TSHRLMNA | |
| Hydrochloric Acid SCHEMBL11549840 | 0.84 | CASP6 (0.68) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL29559211 | 0.84 | MAPT (0.56) | CASP6TSHRLMNA | |
| SCHEMBL11466888 | 0.83 | VCAM1 (0.68) | CASP6LMNAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694178-A | Dabigatran etexilate analog centered by fluorine-containing-group-modified benzene ring and synthesis method thereof | SHANGHAI INST TECHNOLOGY | 2014-04-02 | — | — | CN | claimed |
| CN-103694224-A | Dabigatran etexilate analog centered by fluorine-containing-group-modified benzene ring and synthesis method thereof | SHANGHAI INST TECHNOLOGY | 2014-04-02 | — | — | CN | claimed |
| CN-103288744-A | Fluorine group-containing-modified dabigatran etexilate analogue and synthetic method thereof | SHANGHAI INST TECHNOLOGY | 2013-09-11 | — | — | CN | claimed |
| CN-103242296-A | Dabigatran etexilate analogue with fluorine-containing group modified pyridine ring as center and synthesis method of analogue | SHANGHAI INST TECHNOLOGY | 2013-08-14 | — | — | CN | claimed |
| CN-103224469-A | Pradaxa analogue with fluorine-containing group modified benzene ring as center and synthesis method thereof | SHANGHAI INST TECHNOLOGY | 2013-07-31 | — | — | CN | claimed |
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-117338950-A | Polymer material for reducing cardiac toxicity of anthracycline chemotherapeutics and application thereof | 天津大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-115232126-B | Beta-carbolin-1, 2, 3-triazole compound, preparation method thereof and application of compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-04-25 | — | — | CN | disclosed |
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| US-11548894-B2 | Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-10 | — | — | US | disclosed |
| US-11548894-B2 | Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-10 | — | — | US | disclosed |
| EP-0187231-A2 | Amino phenyl benzothiazoles | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| US-4461888-A | OPTICAL FILTERS | POLAROID CORPORATION (US) | 1984-07-24 | — | — | US | disclosed |
| US-4461886-A | AROMATIC POLYAMIDES CONTAINING HALO, NITRO OR UNSATURATED SUBSTITUENTS; FILMS; FIBERS | POLAROID CORPORATION (US) | 1984-07-24 | — | — | US | disclosed |
| US-4384107-A | MOLECULAR ORIENTATION | POLAROID CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |
| EP-0001246-B1 | PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES | CASSELLA Aktiengesellschaft (DE) | 1981-02-25 | — | — | EP | disclosed |
| US-4192947-A | REACTING DIAMINO NITROBENZENE WITH NITROBENZOYL CHLORIDE, CYCLIZING ANILIDE IN AQUEOUS ALKALI, REDUCING NITRO GROUPS WITH SULFIDE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-11 | — | — | US | disclosed |
| EP-0001246-A1 | Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles | CASSELLA Aktiengesellschaft (DE) | 1979-04-04 | — | — | EP | disclosed |
| US-4036838-A | Process for the production of nitro derivatives of aromatic compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548894-B2 | Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers | ACAT1, ACAT2, NPC1L1 | CASP6 1102/4885TSHR 4433/4885LMNA 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.