Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | GCK | P35557 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856496 | 0.82 | MEN1 (0.44) | KCNMA1KDM4ENPC1KMT2AMAPT | |
| SCHEMBL6215480 | 0.81 | MALT1 (0.53) | MALT1 | |
| SCHEMBL2852163 | 0.81 | KMT2A (0.53) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2855512 | 0.80 | MALT1 (0.55) | KCNMA1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL2857034 | 0.79 | KDM4E (0.62) | ALDH1A1KDM4ENPC1KMT2AMAPT | |
| SCHEMBL2852931 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ENPC1KMT2AMAPT | |
| SCHEMBL28696410 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4ENPC1KMT2AMAPT | |
| SCHEMBL2860841 | 0.78 | DHODH (0.55) | ALDH1A1KDM4ENPC1KMT2AMAPT | |
| SCHEMBL2856075 | 0.77 | NAMPT (0.56) | KCNMA1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL2860428 | 0.77 | KDM4E (0.52) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |