Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852244 | 0.83 | MAPT (0.48) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2860432 | 0.82 | KCNMA1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2852516 | 0.82 | MALT1 (0.39) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL2859029 | 0.82 | FFAR2 (0.46) | MEN1KMT2AMAPTSMN1; SMN2CASP3 | |
| SCHEMBL2850524 | 0.81 | MAPT (0.43) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2854992 | 0.81 | L3MBTL1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2860795 | 0.81 | KMT2A (0.46) | MEN1KMT2AMAPTSMN1; SMN2FFAR2 | |
| SCHEMBL2848317 | 0.80 | MAPT (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2857584 | 0.80 | RAB9A (0.45) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL2850728 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |