Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854852 | 0.89 | ABCB1 (0.49) | NAMPTEPHX1GAAKMT2ADHODH | |
| SCHEMBL2855714 | 0.84 | EPHX1 (0.45) | NAMPTEPHX1KMT2AMAPK1 | |
| SCHEMBL2857357 | 0.81 | HTT (0.46) | NAMPTEPHX1GAAKMT2AMAPK1 | |
| SCHEMBL2861243 | 0.81 | KDM4E (0.52) | NPC1RAB9AKMT2A | |
| SCHEMBL2852520 | 0.81 | TP53 (0.47) | NPC1RAB9AGAAKMT2ADHODH | |
| SCHEMBL2850427 | 0.80 | SMN1; SMN2 (0.60) | TRPV1GAAKMT2A | |
| SCHEMBL2852635 | 0.80 | EPHX1 (0.44) | NAMPTEPHX1NPC1KMT2AMAPK1 | |
| SCHEMBL2853193 | 0.80 | MAPT (0.43) | NAMPTNPC1RAB9AGAAKMT2A | |
| SCHEMBL2854804 | 0.79 | MAPK1 (0.48) | RAB9AMAPK1 | |
| SCHEMBL2860715 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |