Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857357 | 0.87 | HTT (0.46) | EPHX1NAMPTMEN1KMT2AMAPK1 | |
| SCHEMBL2853347 | 0.87 | TRPV1 (0.41) | — | |
| SCHEMBL2854852 | 0.85 | ABCB1 (0.49) | EPHX1NAMPTMEN1KMT2AMCHR1 | |
| SCHEMBL2855714 | 0.84 | EPHX1 (0.45) | EPHX1NAMPTMEN1KMT2AMAPK1 | |
| SCHEMBL2861682 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AMAPK1 | |
| SCHEMBL2859504 | 0.80 | TAAR1 (0.43) | MEN1KMT2ANPC1 | |
| SCHEMBL2852553 | 0.80 | MALT1 (0.40) | MEN1KMT2ANPC1NPSR1 | |
| SCHEMBL2854467 | 0.80 | MAPT (0.36) | — | |
| SCHEMBL2860435 | 0.80 | NAMPT (0.46) | EPHX1NAMPTKMT2AMAPK1NPC1 | |
| SCHEMBL2850252 | 0.79 | TRPV1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |