Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599524 | 0.85 | ALDH1A1 (0.58) | PKMALDH1A1GAAUSP2TSHR | |
| SCHEMBL28606322 | 0.84 | USP2 (0.52) | PKMALDH1A1GAAUSP2KDM4E | |
| SCHEMBL28601239 | 0.81 | HTT (0.49) | PKMALDH1A1GAATSHRLMNA | |
| SCHEMBL28611268 | 0.80 | CA1 (0.44) | ALDH1A1GAAUSP2KDM4ENPSR1 | |
| SCHEMBL29720703 | 0.79 | CA2 (0.43) | PKMALDH1A1LMNA | |
| SCHEMBL28618856 | 0.75 | ALDH1A1 (0.56) | PKMALDH1A1GAAUSP2TSHR | |
| SCHEMBL28617316 | 0.74 | CA1 (0.43) | ALDH1A1GAA | |
| SCHEMBL28618201 | 0.73 | F2 (0.44) | ALDH1A1GAAUSP2 | |
| SCHEMBL28618855 | 0.69 | MAPT (0.46) | ALDH1A1GAAUSP2KDM4ENPSR1 | |
| SCHEMBL29720620 | 0.69 | F10 (0.41) | PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105395-B | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113105395-A | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2021-07-13 | — | — | CN | disclosed |