Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642608 | 0.83 | L3MBTL1 (0.39) | PIK3C3RAPGEF4BRD4 | |
| SCHEMBL31465621 | 0.82 | RAPGEF4 (0.36) | PIK3C3RAPGEF4FABP4BRD4CTSG | |
| SCHEMBL23403832 | 0.82 | RAPGEF4 (0.36) | PIK3C3RAPGEF4FABP4BRD4CTSG | |
| SCHEMBL28802488 | 0.80 | CYP2C19 (0.36) | PIK3C3 | |
| SCHEMBL16923791 | 0.77 | PIK3C3 (0.54) | PIK3C3RAPGEF4FABP4BRD4CTSG | |
| SCHEMBL28657465 | 0.77 | RAPGEF4 (0.37) | PIK3C3RAPGEF4FABP4 | |
| SCHEMBL23668185 | 0.75 | PIK3C3 (0.33) | PIK3C3RAPGEF4 | |
| SCHEMBL28604693 | 0.73 | RAPGEF4 (0.35) | RAPGEF4FABP4CTSGCMA1 | |
| SCHEMBL28852705 | 0.73 | FABP4 (0.45) | RAPGEF4FABP4 | |
| SCHEMBL14677903 | 0.72 | RAPGEF4 (0.33) | PIK3C3RAPGEF4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153646-B | Pyridine dicarboxamide derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2022-08-02 | — | — | CN | disclosed |