Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | CCR1 | P32246 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861423 | 0.93 | P2RX7 (0.46) | P2RX7CCR1POLBUSP30NPSR1 | |
| SCHEMBL2857989 | 0.87 | P2RX7 (0.49) | P2RX7CCR1POLBKDM4E | |
| SCHEMBL2859091 | 0.86 | CCR1 (0.46) | P2RX7CCR1SMO | |
| SCHEMBL2863210 | 0.85 | CCR1 (0.50) | P2RX7CCR1KDM4ENPSR1SMO | |
| SCHEMBL2853351 | 0.85 | CCR1 (0.62) | P2RX7CCR1KDM4ENPSR1 | |
| SCHEMBL2853354 | 0.84 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL2852356 | 0.83 | CCR1 (0.48) | P2RX7CCR1KDM4ENPSR1SMO | |
| SCHEMBL2861063 | 0.83 | CCR1 (0.57) | P2RX7CCR1KDM4ENPSR1 | |
| SCHEMBL2854563 | 0.82 | P2RX7 (0.57) | P2RX7CCR1POLBKDM4E | |
| SCHEMBL2852117 | 0.82 | P2RX7 (0.48) | P2RX7CCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |