Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858268 | 0.93 | P2RX7 (0.48) | P2RX7CACNA1GCACNA1HKDM4EALDH1A1 | |
| SCHEMBL2853063 | 0.90 | P2RX7 (0.48) | P2RX7NR3C1CCR1CACNA1GCACNA1H | |
| SCHEMBL2857989 | 0.90 | P2RX7 (0.49) | P2RX7NR3C1CCR1CACNA1GCACNA1H | |
| SCHEMBL2853354 | 0.89 | P2RX7 (0.63) | P2RX7LMNA | |
| SCHEMBL2852117 | 0.88 | P2RX7 (0.48) | P2RX7CCR1CACNA1GCACNA1HALDH1A1 | |
| SCHEMBL2850369 | 0.86 | P2RX7 (0.56) | P2RX7NR3C1CCR1PKMTP53 | |
| SCHEMBL2854804 | 0.86 | MAPK1 (0.48) | P2RX7CCR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2850425 | 0.84 | P2RX7 (0.49) | P2RX7CCR1TP53POLBMAPT | |
| SCHEMBL2856615 | 0.84 | P2RX7 (0.48) | P2RX7CCR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2854847 | 0.84 | ALDH1A1 (0.48) | P2RX7CCR1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |