Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011086 | 0.86 | PTGDR2 (0.45) | ALDH1A1TSHRKDM4EATMPTGDR2 | |
| SCHEMBL28622483 | 0.83 | PTGDR2 (0.48) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL8388005 | 0.80 | PTGDR2 (0.51) | ALDH1A1TSHRATMGAAPTGDR2 | |
| SCHEMBL11836306 | 0.80 | AKR1C3 (0.48) | ALDH1A1TSHRKDM4EGAAPTGDR2 | |
| SCHEMBL11828886 | 0.78 | LMNA (0.49) | ALDH1A1TSHRPTGDR2MEN1KMT2A | |
| SCHEMBL5810777 | 0.77 | PTGDR2 (0.48) | ALDH1A1KDM4EATMPTGDR2MEN1 | |
| SCHEMBL28605187 | 0.76 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL2165481 | 0.73 | ALDH1A1 (0.67) | ALDH1A1TSHRKDM4EATMGAA | |
| SCHEMBL28609601 | 0.73 | HDAC1 (0.43) | PTGDR2 | |
| SCHEMBL2530097 | 0.72 | KDM4E (0.52) | ALDH1A1TSHRTDP1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |