Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388005 | 0.84 | PTGDR2 (0.51) | PTGDR2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL13011086 | 0.80 | PTGDR2 (0.45) | PTGDR2KDM4EALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL2530097 | 0.78 | KDM4E (0.52) | PTGDR2KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL11836306 | 0.78 | AKR1C3 (0.48) | PTGDR2KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL2313013 | 0.78 | KDM4E (0.59) | PTGDR2KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL28607228 | 0.77 | ALDH1A1 (0.46) | PTGDR2KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL4726921 | 0.77 | SCARB1 (0.46) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7590610 | 0.77 | KDM4E (0.53) | PTGDR2KDM4EALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7586679 | 0.77 | KDM4E (0.53) | PTGDR2KDM4EALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL11828886 | 0.76 | LMNA (0.49) | PTGDR2ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |