Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31234771 | 0.82 | CA2 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27166746 | 0.79 | CA2 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27166753 | 0.79 | CA2 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1547978 | 0.79 | ALDH1A1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| Acetic Acid SCHEMBL8120218 | 0.79 | ALDH1A1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28614173 | 0.78 | MMP2 (0.53) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL28614175 | 0.78 | MMP2 (0.53) | CA1CA2F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7362391 | 0.78 | ALDH1A1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL21994408 | 0.77 | POLB (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30800487 | 0.76 | CA2 (0.67) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335081-A | Targeted plasma protein degradation | 诺华股份有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113166101-A | Cyclic pentameric compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |