Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614173 | 1.00 | MMP2 (0.53) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL10012970 | 0.80 | ALDH1A1 (0.46) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL28607609 | 0.78 | CA1 (0.47) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL21995283 | 0.77 | MMP2 (0.60) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL21995282 | 0.77 | MMP2 (0.60) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL8575008 | 0.75 | CA2 (0.65) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL22492652 | 0.75 | MMP2 (0.68) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL5193258 | 0.75 | MMP2 (0.68) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL30191314 | 0.73 | MMP2 (0.50) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL6422533 | 0.72 | MMP2 (0.92) | MMP2MMP9MMP1MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166101-A | Cyclic pentameric compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |