SCHEMBL2860776

SCHEMBL2860776

Cc1c(O)cccc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 2/20 0.62
HPGD P15428 1/20 0.62
BCL2L1 Q07817 1/20 0.62
PDCD1 Q15116 1/20 0.59
CD274 Q9NZQ7 1/20 0.59
BACE1 P56817 3/20 0.52
TRPA1 O75762 2/20 0.50
ATM Q13315 1/20 0.50
ESR2 Q92731 1/20 0.45
ALOX5 P09917 1/20 0.45
HNF4A P41235 1/20 0.44
CA12 O43570 1/20 0.44
TNF P01375 1/20 0.44
CA9 Q16790 1/20 0.44
NOD2 Q9HC29 1/20 0.44
NOD1 Q9Y239 1/20 0.44
HDAC4 P56524 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC8 Q9BY41 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636457 1.00 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL25470904 0.96 BCL2L1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL27749171 0.87 HPGD (0.64) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL30642011 0.84 TRPA1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL28821934 0.84 TRPA1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL30046939 0.84 TRPA1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1PDCD1
SCHEMBL16528177 0.83 TRPA1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1TRPA1
SCHEMBL31344496 0.83 TRPA1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1TRPA1
SCHEMBL29436302 0.83 TRPA1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1TRPA1
SCHEMBL25785668 0.83 PDCD1 (0.64) ALDH1A1HSD17B10HPGDBCL2L1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101226176-B Method for measuring boilling point distribution of coal and rock oil deriving heavy oil products with liquid phase chromatography INST COAL CHEMISTRY CAS 2011-09-21 CN claimed
CN-101226176-A Method for measuring boilling point distribution of coal and rock oil deriving heavy oil products with liquid phase chromatography SHANXI COAL CHEM INST (CN) 2008-07-23 CN claimed
CN-1856461-A Cycloalkylene compounds as estrogen receptor modulators SMITHKLINE BEECHAM CORP (US) 2006-11-01 CN claimed
EP-4748825-A1 ACRYLIC ACID DERIVATIVE AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2026-05-27 EP disclosed
EP-3862165-B1 BIAXIALLY ORIENTED POLYAMIDE FILM AND POLYAMIDE FILM MILL ROLL TOYO BOSEKI (JP) 2025-08-06 EP disclosed
US-12378205-B2 Process for the preparation of triazine intermediates and a process for the preparation of UV absorbers thereof BASF SE (DE) 2025-08-05 US disclosed
US-12291509-B2 Process for the preparation of UV absorbers BASF SE (DE) 2025-05-06 US disclosed
WO-2025018374-A1 ACRYLIC ACID DERIVATIVE AND USE THEREOF 住友化学株式会社 2025-01-23 WO disclosed
US-11999849-B2 Biaxially oriented polyamide film and polyamide film mill roll TOYOBO CO., LTD. (JP) 2024-06-04 US disclosed
CN-113302172-B Enantioselective preparation of chiral tetraarylmethanes 香港科技大学 2023-12-01 CN disclosed
US-20230226062-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2023-07-20 US disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
EP-0032060-B1 NOVOLAK RESIN COMPOSITION AND PRODUCTS FORMED THEREFROM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP disclosed
US-4465816-A GRAFT POLYMER WITH THIO ACID PARKER CHEMICAL COMPANY (US) 1984-08-14 US disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
US-4342852-A Setting type resin composition containing a substantially linear, high-molecular-weight novolak substituted phenolic resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-03 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed
US-4230746-A SULFATE FOAMING AGENT, TERTIARY AMINE OR QUATERNARY SALT DISPERSANT, SULFOSUCCINATE STABILIZER GAF CORPORATION (US) 1980-10-28 US disclosed
US-4208485-A ORGANIC SULFATE, SULFOSUCCINIC ACID DERIVATIVES, AND AN ALKYLENEOXY AMINE GAF CORPORATION (US) 1980-06-17 US disclosed
US-4198316-A Foaming composition for textile finishing and coatings GAF CORPORATION (US) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378205-B2 Process for the preparation of triazine intermediates and a process for the preparation of UV absorbers thereof DHPS, UNG, UMPS ALDH1A1 606/4885HSD17B10 1297/4885HPGD 310/4885
US-12291509-B2 Process for the preparation of UV absorbers UNG, UROD, ERCC4 ALDH1A1 673/4885HSD17B10 1737/4885HPGD 249/4885
US-20230226062-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS CD274, PDCD1, PDCD1LG2 ALDH1A1 122/4885HSD17B10 2086/4885HPGD 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.