Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642486 | 0.90 | CFTR (0.51) | CFTRCDK2ALDH1A1KDM4EMAPT | |
| SCHEMBL28496945 | 0.86 | KDM4E (0.49) | CDK2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30120650 | 0.86 | KDM4E (0.49) | CDK2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19579754 | 0.85 | CFTR (0.49) | CFTRCDK2ALDH1A1KDM4EHPGD | |
| SCHEMBL28602079 | 0.82 | PLA2G2A (0.58) | ALDH1A1KDM4EHPGDHSD17B10DHODH | |
| SCHEMBL28100426 | 0.81 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28130384 | 0.80 | KDM4E (0.68) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28100420 | 0.80 | PLA2G2A (0.58) | CDK2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28100530 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28100421 | 0.78 | NQO2 (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106380446-B | Synthesis method of quinoline-2 formate derivative | 南阳师范学院 | 2021-06-18 | — | — | CN | disclosed |