Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | PNMT | P11086 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629335 | 1.00 | ADRA2A (0.40) | ADRA2APNMTADRA2BADRA2CPBRM1 | |
| SCHEMBL28596610 | 0.88 | ADRA2A (0.40) | ADRA2APNMTADRA2BADRA2CPBRM1 | |
| SCHEMBL29629340 | 0.88 | ADRA2A (0.40) | ADRA2APNMTADRA2BADRA2CPBRM1 | |
| SCHEMBL28988617 | 0.83 | MAOB (0.39) | HTR2AHTR2CHTR2BSIRT2METAP1 | |
| SCHEMBL29629329 | 0.83 | MAOB (0.39) | HTR2AHTR2CHTR2BSIRT2METAP1 | |
| SCHEMBL28585902 | 0.83 | MAOB (0.39) | HTR2AHTR2CHTR2BSIRT2METAP1 | |
| SCHEMBL28988605 | 0.82 | ACHE (0.40) | HIF1AOPRM1OPRK1 | |
| SCHEMBL30367349 | 0.82 | ACHE (0.40) | HIF1AOPRM1OPRK1 | |
| SCHEMBL30367476 | 0.79 | ALDH1A1 (0.37) | NFKB1 | |
| SCHEMBL28596564 | 0.78 | PPARG (0.40) | SIRT1ATMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-112898259-B | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-112898259-A | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2021-06-04 | — | — | CN | disclosed |