Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 11/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988605 | 1.00 | ACHE (0.40) | ACHEMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL28585902 | 0.83 | MAOB (0.39) | ACHEMAOB | |
| SCHEMBL28988617 | 0.83 | MAOB (0.39) | ACHEMAOB | |
| SCHEMBL29629329 | 0.83 | MAOB (0.39) | ACHEMAOB | |
| SCHEMBL29629335 | 0.82 | ADRA2A (0.40) | OPRM1OPRK1HIF1A | |
| SCHEMBL28608348 | 0.82 | ADRA2A (0.40) | OPRM1OPRK1HIF1A | |
| SCHEMBL27985951 | 0.80 | MAOB (0.35) | ACHEMAOB | |
| SCHEMBL30367476 | 0.79 | ALDH1A1 (0.37) | PPARGPPARA | |
| SCHEMBL30374028 | 0.78 | ACHE (0.40) | ACHEMAOBPPARGPPARAHIF1A | |
| SCHEMBL28596563 | 0.78 | PPARG (0.40) | ACHEMAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |