Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612447 | 0.91 | MEN1 (0.43) | LIG1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28601603 | 0.87 | MAPT (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28610945 | 0.86 | TGM2 (0.41) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL28606032 | 0.85 | GRIK1 (0.41) | LIG1MEN1KMT2A | |
| SCHEMBL28599139 | 0.84 | GRIK1 (0.40) | LIG1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28614923 | 0.84 | GRIK1 (0.40) | LIG1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28599093 | 0.83 | LIG1 (0.39) | LIG1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28603927 | 0.82 | MAOB (0.43) | MAPTPOLB | |
| SCHEMBL28603953 | 0.80 | KDM4E (0.48) | MAPTKDM4E | |
| SCHEMBL1501817 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |