Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601603 | 0.92 | MAPT (0.50) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL28608488 | 0.91 | LIG1 (0.51) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL28610945 | 0.91 | TGM2 (0.41) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL28603953 | 0.88 | KDM4E (0.48) | KDM4EMAPT | |
| SCHEMBL28603927 | 0.87 | MAOB (0.43) | MAPTMDM2 | |
| SCHEMBL3731761 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL28600852 | 0.81 | HTT (0.43) | ALDH1A1LMNAHPGDKDM4EGAA | |
| SCHEMBL28614923 | 0.80 | GRIK1 (0.40) | MEN1KMT2ALMNALIG1 | |
| SCHEMBL28599139 | 0.80 | GRIK1 (0.40) | MEN1KMT2ALMNALIG1 | |
| SCHEMBL28612682 | 0.76 | PBRM1 (0.41) | TGM2CES1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |