Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25871487 | 0.89 | PAM (0.53) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL28618838 | 0.89 | PAM (0.53) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL11831935 | 0.84 | NPC1 (0.56) | KMT2AMEN1NPC1RAB9AHSD11B1 | |
| SCHEMBL727447 | 0.82 | HSD11B1 (0.50) | KMT2ARAB9ANFE2L2HSD11B1MAPT | |
| SCHEMBL727448 | 0.82 | HSD11B1 (0.50) | KMT2ARAB9ANFE2L2HSD11B1MAPT | |
| SCHEMBL2043779 | 0.82 | HSD11B1 (0.50) | KMT2ARAB9ANFE2L2HSD11B1MAPT | |
| SCHEMBL28606283 | 0.81 | BCHE (0.58) | KMT2AMEN1NPC1RAB9ASNCA | |
| SCHEMBL28608432 | 0.79 | HDAC1 (0.56) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL28454162 | 0.79 | L3MBTL1 (0.58) | KMT2ANPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL28839596 | 0.77 | PTGS2 (0.43) | KMT2AL3MBTL1MAPTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112500270-B | Method for synthesizing alpha, alpha-difluoroketone compound | 台州学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-112500270-A | Method for synthesizing alpha, alpha-difluoroketone compound | 台州学院 | 2021-03-16 | — | — | CN | disclosed |