Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21796877 | 1.00 | TRPV3 (0.41) | TRPV3GPR119ALKRXRARXRB | |
| SCHEMBL18399288 | 1.00 | TRPV3 (0.41) | TRPV3GPR119ALKRXRARXRB | |
| SCHEMBL18399199 | 0.92 | GPR119 (0.40) | TRPV3GPR119RXRARXRBRXRG | |
| SCHEMBL21796615 | 0.92 | GPR119 (0.40) | GPR119ALKRXRARXRBRXRG | |
| SCHEMBL28610193 | 0.92 | GPR119 (0.40) | TRPV3GPR119RXRARXRBRXRG | |
| SCHEMBL22723340 | 0.92 | GPR119 (0.40) | GPR119ALKRXRARXRBRXRG | |
| SCHEMBL22873547 | 0.92 | GPR119 (0.40) | TRPV3GPR119RXRARXRBRXRG | |
| SCHEMBL20437475 | 0.92 | GPR119 (0.40) | GPR119ALKRXRARXRBRXRG | |
| SCHEMBL31084354 | 0.91 | GPR119 (0.39) | GPR119ALKRXRARXRBRXRG | |
| SCHEMBL28608218 | 0.87 | RXRA (0.45) | GPR119RXRARXRBRXRGCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137510-B | Compound (I) | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-20 | — | — | CN | disclosed |