Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962953 | 0.77 | LMNA (0.41) | CA12CA7CA14CA9CA1 | |
| SCHEMBL21962948 | 0.75 | LMNA (0.39) | CA12CA7CA14CA9ALDH1A1 | |
| SCHEMBL25014616 | 0.69 | KCNN4 (0.37) | CA12CA7CA14CA1HTT | |
| SCHEMBL21962888 | 0.68 | GAA (0.38) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL22266027 | 0.67 | KEAP1 (0.41) | ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL22266023 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL25014712 | 0.64 | GAA (0.32) | CA9CA1NR1I2ALDH1A1HTT | |
| SCHEMBL7760178 | 0.62 | HDAC3 (0.37) | ALDH1A1POLBMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21962677 | 0.62 | CA12 (0.55) | CA12CA9CA1ALDH1A1LMNA | |
| SCHEMBL22010517 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166081-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |