Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085241 | 0.79 | HTT (0.43) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL27967508 | 0.75 | HTT (0.40) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL28608961 | 0.72 | HTT (0.38) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL28608301 | 0.71 | ALDH1A1 (0.45) | HTTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28605665 | 0.71 | ALDH1A1 (0.45) | HTTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28600764 | 0.70 | HPGD (0.36) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL4744678 | 0.69 | CRHR1 (0.50) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL4745138 | 0.66 | KMT2A (0.42) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL437497 | 0.66 | NR4A2 (0.62) | HTTKMT2AMEN1BCHEACHE | |
| SCHEMBL26998821 | 0.65 | BCHE (0.42) | HTTKMT2AMEN1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004210-A | Quinazoline-4-selenium salt compound, preparation method and biological activity | 鲁东大学 | 2021-06-22 | — | — | CN | disclosed |