Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744678 | 0.82 | CRHR1 (0.50) | KMT2AMEN1MAPTNR4A2HTT | |
| SCHEMBL11386180 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL437497 | 0.78 | NR4A2 (0.62) | KMT2AMEN1MAPTNR4A2HTT | |
| SCHEMBL1026984 | 0.76 | NR4A2 (0.65) | MAPTNR4A2CRHR1L3MBTL1CYP3A4 | |
| SCHEMBL10969359 | 0.74 | CYP1A2 (0.43) | KMT2AMEN1HTTALDH1A1TSHR | |
| SCHEMBL4768328 | 0.73 | MAPT (0.49) | KMT2AMEN1MAPTNR4A2HTT | |
| SCHEMBL3799140 | 0.71 | OPRK1 (0.50) | KMT2AMAPTNR4A2HTTALDH1A1 | |
| SCHEMBL5250469 | 0.71 | CRHR1 (0.77) | MAPTNR4A2CRHR1L3MBTL1HSP90AA1 | |
| SCHEMBL9680093 | 0.70 | BCHE (0.37) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL10435140 | 0.70 | MAPT (0.39) | KMT2AMEN1MAPTNR4A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |