SCHEMBL28609062

SCHEMBL28609062

CC1(C)COC(CBr)(c2ccc(F)cc2)OC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.39
SLC6A2 P23975 2/20 0.39
CHRNA1 P02708 1/20 0.39
CHRNG P07510 1/20 0.39
CHRNB1 P11230 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRND Q07001 1/20 0.39
EGFR P00533 1/20 0.38
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.35
GRIN1 Q05586 1/20 0.34
GRIN2B Q13224 1/20 0.34
SLC6A4 P31645 2/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
PABPC1 P11940 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121397 0.82 EGFR (0.41) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL10852241 0.80 SLC6A2 (0.41) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL7879929 0.79 GRIN1 (0.40) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL3395753 0.78 GRIN1 (0.41) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL4689099 0.73 HSD11B1 (0.42) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL4689021 0.70 GRIN1 (0.40) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL11239184 0.69 CHRNA1 (0.35) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL991292 0.69 SLC6A3 (0.47) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL11243351 0.68 CHRNA1 (0.35) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL12132777 0.67 MAOB (0.34) EGFRMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234066-A Propiconazole-like compound and preparation method and application thereof 浙江工业大学 2021-08-10 CN disclosed