Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRND | Q07001 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499439 | 0.87 | CHRNB2 (0.35) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL3509939 | 0.78 | SLC6A2 (0.47) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL11489793 | 0.76 | OPRM1 (0.34) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL8907842 | 0.76 | SLC6A3 (0.46) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL8906999 | 0.76 | SLC6A3 (0.46) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL990597 | 0.76 | SLC6A4 (0.47) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14142801 | 0.76 | TAAR1 (0.47) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL3209284 | 0.76 | TAAR1 (0.47) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL5698923 | 0.76 | MAOA (0.46) | SLC6A3SLC6A2MAOBMAOALMNA | |
| SCHEMBL5698924 | 0.76 | MAOA (0.46) | SLC6A3SLC6A2MAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080719-A | Preparation method of polysubstituted olefin epoxy compound | 广西科技大学 | 2024-12-06 | — | — | CN | disclosed |
| US-9550782-B2 | Compounds and methods for treating diabetes | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-9527854-B2 | Compounds and methods for treatment of hypertension | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9481676-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-9469641-B2 | Pyrido[3,4-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| CN-103476416-B | The Compounds and methods for for the treatment of hypertension | 梅迪维新技术公司 | 2016-09-21 | — | — | CN | disclosed |
| US-9409910-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| EP-1080062-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXYALKYL HALOPHENONES | AVECIA LTD (GB) | 2003-12-10 | — | — | EP | disclosed |
| US-6362376-B1 | 2-BENZYLOXYALKYL HALOPHENONES AS CHIRAL INTERMEDIATES FOR 2-HYDROXYALKL HALOPHENONES | AVECIA LIMITED (GB) | 2002-03-26 | — | — | US | disclosed |
| US-6300522-B1 | CONDENSING 2-CHLOROALKANOIC ACID WITH OPTIONALLY SUBSTITUTED BENZYL ALCOHOL TO FORM 2-BENZYLOXYALKANOIC ACID, CONVERTING TO ACID CHLORIDE, REACTING WITH GRIGNARD REAGENT IN PRESENCE OF CUPROUS COMPOUND, HYDROGENATING TO REMOVE BENZYL GROUP | AVECIA LIMITED (GB) | 2001-10-09 | — | — | US | disclosed |
| EP-1080062-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXYALKYL HALOPHENONES | Avecia Limited (GB) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054272-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXYALKYL HALOPHENONES | AVECIA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |