Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398983 | 1.00 | LRRK2 (0.40) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL20437352 | 1.00 | LRRK2 (0.40) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL18399060 | 0.94 | RXRA (0.40) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL22873493 | 0.94 | RXRA (0.40) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL28606491 | 0.94 | RXRA (0.40) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL18399199 | 0.93 | GPR119 (0.40) | GPR119RXRARXRBRXRGCCNK | |
| SCHEMBL28610193 | 0.93 | GPR119 (0.40) | GPR119RXRARXRBRXRGCCNK | |
| SCHEMBL22873547 | 0.93 | GPR119 (0.40) | GPR119RXRARXRBRXRGCCNK | |
| SCHEMBL31084394 | 0.91 | GPR119 (0.39) | LRRK2GPR119RXRARXRBRXRG | |
| SCHEMBL20437475 | 0.91 | GPR119 (0.40) | GPR119RXRARXRBRXRGCCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137510-B | Compound (I) | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-20 | — | — | CN | disclosed |