Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145134 | 0.81 | LRRK2 (0.42) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL4807592 | 0.74 | ALDH1A1 (0.67) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL10887133 | 0.72 | PIK3CA (0.48) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL12179269 | 0.71 | LRRK2 (0.52) | ALDH1A1POLBLRRK2CYP1A2KDM4E | |
| SCHEMBL21921211 | 0.71 | LRRK2 (0.52) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL15473883 | 0.71 | LRRK2 (0.51) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL14878640 | 0.70 | ALOX15 (0.46) | ALDH1A1POLBHSD17B10ALOX15CYP1A2 | |
| SCHEMBL28556258 | 0.69 | LRRK2 (0.50) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL23328004 | 0.68 | LRRK2 (0.49) | ALDH1A1POLBLRRK2MEN1KMT2A | |
| SCHEMBL23327900 | 0.68 | KDM4E (0.63) | ALDH1A1POLBLRRK2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467369-B | Biaryl amide compounds as kinase inhibitors | 诺华股份有限公司 | 2021-08-20 | — | — | CN | disclosed |