Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607133 | 0.79 | CYP19A1 (0.48) | LMNAMAPTHPGDMAPK1KDM4E | |
| SCHEMBL28619622 | 0.76 | CYP19A1 (0.43) | LMNAMAPTHPGDMAPK1ALDH1A1 | |
| SCHEMBL28607117 | 0.76 | MAOB (0.44) | LMNAMAPTMAPK1HTTTP53 | |
| SCHEMBL28614063 | 0.76 | CYP1A2 (0.44) | LMNAMAPTMAPK1ALDH1A1TP53 | |
| SCHEMBL28414867 | 0.75 | ESR2 (0.53) | LMNAMAPTHPGDALDH1A1TP53 | |
| SCHEMBL28609468 | 0.75 | ALDH1A1 (0.47) | LMNAKIF11TNKSTNKS2PARP3 | |
| SCHEMBL10069656 | 0.74 | KDM4E (0.55) | LMNAKIF11TNKSTNKS2PARP3 | |
| SCHEMBL8117184 | 0.74 | CYP1A2 (0.50) | LMNATNKS2PARP3MAPTHPGD | |
| SCHEMBL28619619 | 0.73 | GPR3 (0.39) | LMNAKIF11MAPTMAPK1ALDH1A1 | |
| SCHEMBL4423401 | 0.73 | ESR2 (0.57) | TNKS2MAPTHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574818-B | Polysubstituted indanone derivative and preparation method thereof | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |