Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184312 | 0.89 | P2RX7 (0.43) | P2RX7ALDH1A1MAPK1 | |
| SCHEMBL20184276 | 0.88 | P2RX7 (0.49) | P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL18880721 | 0.84 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL21819349 | 0.80 | P2RX7 (0.67) | P2RX7IGF1R | |
| SCHEMBL6294533 | 0.74 | P2RX7 (0.54) | P2RX7HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL11982661 | 0.73 | P2RX7 (0.52) | P2RX7ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL21863402 | 0.73 | POLB (0.46) | P2RX7HTR2AHTR2CHTR2BPARP1 | |
| SCHEMBL21818604 | 0.73 | P2RX7 (0.59) | P2RX7PARP1MAPK1 | |
| SCHEMBL29844044 | 0.72 | HTR2A (0.39) | P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL21818614 | 0.70 | P2RX7 (0.73) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |