Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 6/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844019 | 0.80 | KCNK3 (0.40) | P2RX7TDP2BRD4CREBBPSIGMAR1 | |
| SCHEMBL28818532 | 0.79 | P2RX7 (0.46) | HTR2AHTR2CHTR2BP2RX7TDP2 | |
| SCHEMBL20184276 | 0.74 | P2RX7 (0.49) | HTR2AHTR2CHTR2BP2RX7 | |
| SCHEMBL29844133 | 0.74 | C5AR1 (0.46) | P2RX7GRM5BRD4CREBBPKDM2B | |
| SCHEMBL20184312 | 0.73 | P2RX7 (0.43) | P2RX7GRM5CREBBP | |
| Hydrochloric Acid SCHEMBL29844125 | 0.72 | HTR2C (0.46) | HTR2AHTR2CHTR2BTDP2PDE2A | |
| SCHEMBL28612255 | 0.72 | P2RX7 (0.53) | HTR2AHTR2CHTR2BP2RX7 | |
| SCHEMBL30045599 | 0.70 | P2RX7 (0.40) | P2RX7PDE2AGRM5BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL31163475 | 0.69 | HTR2C (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL23577483 | 0.68 | P2RX7 (0.40) | P2RX7BRD4CREBBPKDM2BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |