Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600513 | 0.87 | KMT2A (0.52) | KMT2ALMNASMN1; SMN2MEN1ESR1 | |
| SCHEMBL28605302 | 0.85 | KMT2A (0.60) | KMT2ALMNASMN1; SMN2MEN1ESR1 | |
| SCHEMBL28606571 | 0.84 | SMN1; SMN2 (0.65) | KMT2ALMNASMN1; SMN2MEN1ADCY1 | |
| SCHEMBL28617791 | 0.83 | ALDH1A1 (0.53) | KMT2ALMNASMN1; SMN2MEN1ESR1 | |
| SCHEMBL28607736 | 0.83 | KMT2A (0.60) | KMT2ALMNASMN1; SMN2MEN1ESR1 | |
| SCHEMBL28603715 | 0.82 | LMNA (0.50) | CTSLCTSSCTSKKMT2ALMNA | |
| SCHEMBL28617395 | 0.80 | CTSL (0.51) | CTSLCTSSCTSKCTSBLMNA | |
| SCHEMBL28605930 | 0.78 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1ESR1 | |
| SCHEMBL28609658 | 0.78 | THRB (0.56) | KMT2ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28606577 | 0.78 | KMT2A (0.49) | KMT2ALMNASMN1; SMN2MEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214236-B | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-113214236-A | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2021-08-06 | — | — | CN | disclosed |