Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603932 | 0.94 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2TP53THRB | |
| SCHEMBL28612434 | 0.92 | MAPT (0.42) | RAB9ASMN1; SMN2TP53FPR2FPR1 | |
| SCHEMBL28601605 | 0.89 | KDR (0.39) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28603992 | 0.89 | KDR (0.39) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28606070 | 0.89 | GRIK1 (0.42) | MAOAMAOBNPC1RAB9AHCRTR1 | |
| SCHEMBL28598799 | 0.89 | IDH1 (0.38) | NPC1RAB9ASMN1; SMN2TP53FPR2 | |
| SCHEMBL28598858 | 0.89 | IDH1 (0.38) | NPC1RAB9ASMN1; SMN2TP53FPR2 | |
| Aza-Flavanone SCHEMBL28606333 | 0.88 | MAOA (0.45) | MAOAMAOBSMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL28612665 | 0.87 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2FPR2FPR1 | |
| Aza-Flavanone SCHEMBL28608106 | 0.86 | KDR (0.42) | NPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |