SCHEMBL28612929

SCHEMBL28612929

CC(C)(O)Cl.c1cc2cc(c1)N2

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PGR P06401 1/20 0.31
THRB P10828 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491179 0.78
SCHEMBL4258759 0.73 CA12 (0.33) CA2
Acetonitrile SCHEMBL5023780 0.69 ACHE (0.36) MEN1KMT2A
SCHEMBL28765828 0.69 CYP1A2 (0.30)
SCHEMBL17668348 0.65 MEN1 (0.30) MEN1KMT2ATSHR
SCHEMBL949352 0.63
SCHEMBL5948758 0.60 MAOA (0.38)
Phenol SCHEMBL9073761 0.60 CA2 (0.65) CA2ESR1ESR2TSHR
SCHEMBL45022 0.60 ESR1 (0.44) ESR1ESR2PGK1PGK2TSHR
SCHEMBL304190 0.60 ESR1 (0.50) CA2ESR1ESR2PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762853-B Method for synthesizing isopropanol beta-alkamine derivative on line by lipase catalysis 浙江工业大学 2021-07-27 CN disclosed