Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | PGK1 | P00558 | 2/20 | 0.44 |
| ▸ | PGK2 | P07205 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203013 | 0.92 | HDAC8 (0.47) | ESR1ESR2PGK1PGK2TSHR | |
| SCHEMBL11662186 | 0.88 | TSHR (0.50) | TSHRMAPK1ALDH1A1TAAR1 | |
| SCHEMBL11469047 | 0.85 | CYP19A1 (0.43) | TSHRMAPK1KIF11ALDH1A1CYP1A2 | |
| SCHEMBL11662449 | 0.85 | ACHE (0.50) | MAPK1KIF11ACHEALDH1A1CYP1A2 | |
| SCHEMBL15352176 | 0.83 | ALDH1A1 (0.44) | ESR1ESR2PGK1PGK2TSHR | |
| SCHEMBL45290 | 0.81 | GABRA1 (0.38) | TSHR | |
| SCHEMBL20963008 | 0.79 | HTR2A (0.35) | ESR1ESR2PGK1PGK2MAPK1 | |
| SCHEMBL20963009 | 0.79 | KIF11 (0.46) | PGK1PGK2TSHRHDAC4HDAC2 | |
| SCHEMBL2145301 | 0.79 | ACHE (0.48) | MAPK1KIF11ACHEALDH1A1TAAR1 | |
| SCHEMBL42357 | 0.79 | TSHR (0.58) | ESR1ESR2TSHRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063154-B2 | Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2011-11-22 | — | — | US | claimed |
| US-8013073-B2 | Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds | CHEVRON ORONITE COMPANY LLC (US) | 2011-09-06 | — | — | US | claimed |
| EP-2279214-A1 | PRODUCTION OF VINYLIDENE-TERMINATED POLYOLEFINS VIA QUENCHING WITH MONOSULFIDES | Chevron Oronite Company LLC (US) | 2011-02-02 | — | — | EP | claimed |
| US-7816459-B2 | Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds | CHEVRON ORONITE COMPANY LLC (US) | 2010-10-19 | — | — | US | claimed |
| EP-1803751-B1 | Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds | CHEVRON ORONITE CO (US) | 2010-06-30 | — | — | EP | claimed |
| EP-1803748-B1 | Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds | CHEVRON ORONITE CO (US) | 2010-06-09 | — | — | EP | claimed |
| US-20090318624-A1 | Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2009-12-24 | — | — | US | claimed |
| US-20090247716-A1 | Production of Vinylidene-Terminated Polyolefins Via Quenching with Monosulfides | CHEVRON ORONITE COMPANY LLC | 2009-10-01 | — | — | US | claimed |
| WO-2009120551-A1 | PRODUCTION OF VINYLIDENE-TERMINATED POLYOLEFINS VIA QUENCHING WITH MONOSULFIDES | CHEVRON ORONITE COMPANY LLC (US) | 2009-10-01 | — | — | WO | claimed |
| US-7501476-B2 | contacting a olefin monomer (isobutylene) with an initiator( 2-chloro-2,4,4,-trimethylpentane) in the presence of a Lewis acid and solvent under suitable quasiliving polymerization reaction conditions, contacting quasiliving carbocationically terminated polymer with an oxazole or thiazoles quencher | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | claimed |
| EP-1803741-B1 | Method for preparing polyolefins containing vinylidene groups using azole compounds | CHEVRON ORONITE CO (US) | 2009-01-21 | — | — | EP | claimed |
| US-20070155911-A1 | Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2007-07-05 | — | — | US | claimed |
| US-20070155910-A1 | Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds | CHEVRON ORONITE COMPANY LLC | 2007-07-05 | — | — | US | claimed |
| US-20070155908-A1 | contacting a olefin monomer (isobutylene) with an initiator( 2-chloro-2,4,4,-trimethylpentane) in the presence of a Lewis acid and solvent under suitable quasiliving polymerization reaction conditions, contacting quasiliving carbocationically terminated polymer with an oxazole or thiazoles quencher | CHEVRON ORONITE COMPANY LLC | 2007-07-05 | — | — | US | claimed |
| EP-1803748-A1 | Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds | Chevron Oronite Company LLC (US) | 2007-07-04 | — | — | EP | claimed |
| EP-1803751-A1 | Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds | Chevron Oronite Company LLC (US) | 2007-07-04 | — | — | EP | claimed |
| EP-1803741-A1 | Method for preparing polyolefins containing vinylidene groups using azole compounds | Chevron Oronite Company LLC (US) | 2007-07-04 | — | — | EP | claimed |
| EP-0083685-B1 | MANUFACTURE OF DIISOCYANATES | AMERICAN CYANAMID COMPANY (US) | 1985-03-06 | — | — | EP | claimed |
| JP-9143106-A | — | — | None | — | — | JP | disclosed |
| EP-0164521-A1 | Process for the preparation of polymeric tertiary aralkyl isocyanates from 1,3- or 1,4-bis(1-chloro-1-methylethyl)benzene | AMERICAN CYANAMID COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |