Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628662 | 0.84 | RAB9A (0.34) | PTGES2 | |
| SCHEMBL22266023 | 0.77 | ALDH1A1 (0.33) | NR3C2 | |
| SCHEMBL22266027 | 0.72 | KEAP1 (0.41) | NR3C2 | |
| SCHEMBL25014616 | 0.71 | KCNN4 (0.37) | — | |
| SCHEMBL21962888 | 0.69 | GAA (0.38) | — | |
| SCHEMBL22265966 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL21962953 | 0.69 | LMNA (0.41) | — | |
| SCHEMBL21962948 | 0.67 | LMNA (0.39) | — | |
| SCHEMBL21962605 | 0.66 | NR1I2 (0.39) | NR3C2 | |
| SCHEMBL22280117 | 0.65 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316566-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-27 | — | — | CN | disclosed |