Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614724 | 0.83 | MCL1 (0.51) | MCL1ALDH1A1MAPTL3MBTL1UTS2R | |
| SCHEMBL28603794 | 0.83 | MCL1 (0.51) | MCL1ALDH1A1MAPTL3MBTL1UTS2R | |
| SCHEMBL28919836 | 0.82 | IMPDH2 (0.56) | CTSLCTSBCTSKIMPDH2 | |
| SCHEMBL14064862 | 0.80 | MCL1 (0.48) | MCL1CTSSCTSLCTSBCTSK | |
| SCHEMBL28600679 | 0.77 | MCL1 (0.50) | MCL1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27705377 | 0.76 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28600675 | 0.75 | MCL1 (0.48) | MCL1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12111459 | 0.75 | NPC1 (0.57) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27983605 | 0.74 | MCL1 (0.47) | MCL1ALDH1A1MAPTL3MBTL1UTS2R | |
| SCHEMBL1720194 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |