Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632983 | 0.96 | VDR (0.45) | VDRPTK6CDC25BPTGS2MMP2 | |
| SCHEMBL28615940 | 0.85 | CNR1 (0.47) | VDRPTGS2MEN1KMT2AGAA | |
| SCHEMBL28615232 | 0.81 | LMNA (0.43) | PTGS2MEN1KMT2AGAAEIF2AK2 | |
| SCHEMBL28619501 | 0.81 | CNR1 (0.47) | VDRPTGS2MEN1KMT2AGAA | |
| SCHEMBL28616025 | 0.79 | LMNA (0.49) | MEN1KMT2AEIF2AK2KDM4EMAPT | |
| SCHEMBL28619465 | 0.78 | LMNA (0.49) | VDRMEN1KMT2AEIF2AK2KDM4E | |
| SCHEMBL28620116 | 0.78 | LMNA (0.49) | PTGS2MEN1KMT2AGAAEIF2AK2 | |
| SCHEMBL28624008 | 0.77 | LMNA (0.43) | PTGS2MEN1KMT2AGAAEIF2AK2 | |
| SCHEMBL20074052 | 0.75 | MAPT (0.59) | CDC25BMEN1KMT2AGAAKDM4E | |
| SCHEMBL28620632 | 0.75 | LMNA (0.49) | MEN1KMT2AEIF2AK2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200967-B | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113200967-A | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2021-08-03 | — | — | CN | disclosed |