Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922176 | 0.91 | HDAC1 (0.46) | HDAC1HDAC6ARHIF1AEPAS1 | |
| SCHEMBL18581361 | 0.88 | HDAC6 (0.59) | HDAC1HDAC6HIF1AEPAS1 | |
| SCHEMBL28629242 | 0.87 | CYP2C9 (0.50) | HDAC1HDAC6HIF1AEPAS1SIRT1 | |
| SCHEMBL28623383 | 0.80 | KMT2A (0.44) | SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL28624617 | 0.80 | RORC (0.44) | HIF1AEPAS1SRD5A2PTGER4NPC1 | |
| SCHEMBL28624625 | 0.78 | GAA (0.47) | HDAC1HDAC6HIF1AEPAS1SIRT2 | |
| SCHEMBL6840333 | 0.78 | ALOX5 (0.55) | HDAC1HDAC6PTGER4PTGER2 | |
| SCHEMBL18581263 | 0.77 | HDAC6 (0.51) | HDAC1HDAC6TNIK | |
| SCHEMBL18593256 | 0.76 | KCNH2 (0.43) | HDAC1HDAC6ARPTGER4RAB9A | |
| SCHEMBL28630081 | 0.76 | DGAT1 (0.45) | SRD5A2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |