Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615356 | 0.88 | CNR1 (0.49) | DGAT1FAAHCNR1KMT2AHRH3 | |
| SCHEMBL28626488 | 0.85 | POLB (0.49) | DGAT1SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL28922176 | 0.82 | HDAC1 (0.46) | SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL28624617 | 0.80 | RORC (0.44) | SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL23619094 | 0.79 | ROCK2 (0.44) | RAB9A | |
| SCHEMBL28617165 | 0.78 | SCN9A (0.51) | SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL3625051 | 0.78 | NR1H3 (0.58) | DGAT1FAAHNAAARAB9A | |
| SCHEMBL28615405 | 0.76 | HDAC1 (0.46) | SRD5A2NPC1RAB9AKMT2A | |
| SCHEMBL28615098 | 0.75 | NR1H3 (0.62) | NPC1KMT2A | |
| SCHEMBL30773984 | 0.74 | GPR142 (0.41) | FAAHNAAACNR1HRH3ME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |