Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28747265 | 0.98 | SOAT1 (0.52) | SOAT1TSHRALDH1A1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL27437666 | 0.96 | SOAT1 (0.50) | SOAT1TSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2223429 | 0.85 | TSHR (0.63) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL3635136 | 0.85 | TSHR (0.63) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL8710504 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL675456 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| Hydrochloric Acid SCHEMBL19031025 | 0.83 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL21138457 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL11488922 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL11402027 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072542-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |