Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612645 | 0.87 | DRD2 (0.54) | HTR1AHTR7DRD2HTR2AALDH1A1 | |
| SCHEMBL29675212 | 0.87 | DRD2 (0.54) | HTR1AHTR7DRD2HTR2AALDH1A1 | |
| SCHEMBL28735817 | 0.83 | DRD2 (0.44) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL29675288 | 0.83 | DRD2 (0.44) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL29675216 | 0.83 | DRD2 (0.54) | HTR1AHTR7DRD2HTR2AHTR2C | |
| SCHEMBL28614770 | 0.83 | DRD2 (0.54) | HTR1AHTR7DRD2HTR2AHTR2C | |
| SCHEMBL29995386 | 0.80 | FDPS (0.67) | ALDH1A1CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL28618325 | 0.80 | FDPS (0.67) | ALDH1A1CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL2246767 | 0.79 | FDPS (0.68) | ALDH1A1MAPTHPGDFDPS | |
| SCHEMBL30462823 | 0.79 | FDPS (0.68) | ALDH1A1MAPTHPGDFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292515-A | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |